Empire of the Sun while abstract, is the most realistic strategic simulation of the Pacific War that I have ever played. It does take a while to learn, and some of the rules can be fickle (especially in regards to the Burma/India/China theater). But if you are looking to get a real feel for the problems both sides faced, this is the game to do it. Their are many excellent tutorials on Youtube as pointed out. The best way to start out is with a smaller scenario, and I cant recommend C3I Magazine #30 with the South Pacific game included. It takes Empire of the Sun, and miniaturizes it to just the South Pacific between 42-43. Small unit density, small map, less cards, etc. It's an excellent learning scenario.
Like most Mark Herman games, a bit of time is required to learn them, but they usually reward you with insights into the conflicts he is portraying much more accurately then most other offerings. Mark Hermans Empire of the Sun, and For the People both make it into my top 10 Wargames of all time.